Prof. Dr. med.
Kaspar Z’graggen
Founder and Chief Physician of the Swiss Pancreas Institute
About Prof. Dr. med. Kaspar Z’graggen
Prof. Dr. med. Kaspar Z'graggen is head of the Swiss Pancreas Institute. For 30 years, his field has been surgery of the digestive tract with specialisation in the area of the pancreas. In addition to his activities as a practising surgeon, Kaspar Z'graggen is active in science. For example, he spent two years as a fellow in the Pancreas Research Lab at Harvard Medical School and has been involved in around 100 research projects and scientific publications during his career, primarily on the subject of the pancreas.
Qualifications and specialisations
2003
Full Professorship CHUV, University of Lausanne
2000
Habilitation
1994 – 1996
Inselspital Berne (Prof. M. W. Büchler)
1995
Specialist in Surgery FMH
1993
Visiting Fellow, Dept. of Surgery Ninewells Hospital, University of Dundee / Scotland
1991 – 1993
Tiefenauspital Berne (Prof. F Nöthiger)
1991
Doctorate University of Berne
1989 – 1990
Aarberg Hospital (Dr. C. Klaiber)
1988
Medical studies FMGEMS / ECFMG
1987
Doctor's degree
1981 – 1987
Medical studies Fribourg / Berne
Medical practice
Since 2004
Head of Swiss Pancreas Centre (since 2021 Swiss Pancreas Institute)
Since 2004
Affiliated physician, Beau-Site Institute and Salem Hospital Hirslanden Berne
Sept 2003 – Aug 2004
Director and Chief Physician Clinic for Visceral Surgery and Centre for Transplantation CHUV, University of Lausanne
Oct 2002 – Aug 2003
Head of Surgical Oncology Section Surgical University Hospital Clinic for General, Visceral and Trauma Surgery Heidelberg, Germany
Oct 2001 – Sept 2002
First Senior Physician Surgical University Hospital Clinic for General, Visceral and Trauma Surgery Heidelberg, Germany
1998 – 2001
Senior Physician, Clinic for Visceral and Transplant Surgery Inselspital University of Berne
1993 – 1994
Senior Physician, Surgical Clinic Tiefenauspital Berne
In offices and boards of directors
Since 2007
Swiss Pancreas Foundation
Co-Founder and Vice-President
2014 – 2017
Siloah AG
Board of Directors
Since 2015
Ärztenetzwerk Bern Praxis AG (Doctors' Network Berne)
Board of Directors, since 2021 Chairman of the Board
2014 – 2021
Klinik Beau-Site
Establishment and management of the training centre V1 for visceral surgery
2015
Co-founder World Pancreas Forum
Congress President 2015, 2017, 2020 in Berne
2007 – 2014
Doctors' Network Berne
Co-President
2004 – 2017
Klinik-Beau-Site Berne
Member and President of the Medical Council
Professorships
Since 2022
Swiss Pancreas Institute
2004 – 2021
Swiss Pancreas Centre
2001 – 2003
European Pancreas Centre of the University of Heidelberg, Germany
2003 – 2004
Full Professorship University of Lausanne
Scientific publications
Schuh F, Mihaljevic AL, Probst P, Trudeau MT, Müller PC, Marchegiani G, Besselink MG, Uzunoglu F, Izbicki JR, Falconi M, Fernandez-Del Castillo C, Adham M, Z’graggen K, Friess H, Werner J, Weitz J, Strobel O, Hackert T, Radenkovic D, Kelemen D, Wolfgang C, Miao YI, Shrikhande SV, Lillemoe KD, Dervenis C, Bassi C, Neoptolemos JP, Diener MK, Vollmer CM Jr, Büchler MW. Ann Surg. 2021 Mar 12.
Neoadjuvant Chemotherapy in Pancreatic Cancer: An Appraisal of the Current High-Level Evidence.
Müller PC, Frey MC, Ruzza CM, Nickel F, Jost C, Gwerder C, Hackert T, Z’graggen K, Kessler U.
Pharmacology. 2021;106(3-4):143-153.
Müller PC, Steinemann DC, Chinczewski L, Hatiboglu G, Nickel F, Z’graggen K, Müller-Stich BP.
Surg Endosc. 2018 Jul;32(7):3393-3400
Müller PC, Müller SA, Steinemann DC, Pärli MS, Moltzahn F, Schmid SW, Z’graggen K.
Am J Surg. 2017 Apr;213(4):711-717.
Role of proteomics to differentiate between benign and potentially malignant pancreatic cysts.
Cuoghi A, Farina A, Z’graggen K, Dumonceau JM, Tomasi A, Hochstrasser DF, Genevay M, Lescuyer P, Frossard JL.J
Proteome Res. 2011 May 6;10(5):2664-70
Chronic pancreatitis is associated with disease-specific regulatory T-cell responses.
Schmitz-Winnenthal H, Pietsch DH, Schimmack S, Bonertz A, Udonta F, Ge Y, Galindo L, Specht S, Volk C, Z’graggen K, Koch M, Büchler MW, Weitz J, Beckhove P.
Gastroenterology. 2010 Mar;138(3):1178-88
Ulrich AB, Seiler CM, Z’graggen K, Löffler T, Weitz J, Büchler MW.
Br J Surg. 2008 Oct;95(10):1257-63
Distal pancreatectomy: risk factors for surgical failure in 302 consecutive cases.
Kleeff J, Diener MK, Z’graggen K, Hinz U, Wagner M, Bachmann J, Zehetner J, Müller MW, Friess H, Büchler MW.
Ann Surg. 2007 Apr;245(4):573-82
Schmitz-Winnenthal FH, Escobedo LV, Beckhove P, Schirrmacher V, Bucur M, Ziouta Y, Volk C, Schmied B, Koch M, Antolovic D, Weitz J, Büchler MW, Z’graggen K.
Int J Oncol. 2006 Jun;28(6):1419-28
Expression of cytokeratin-20 in pancreatic cancer: an indicator of poor outcome after R0 resection.
Schmitz-Winnenthal FH, Volk C, Helmke B, Berger S, Hinz U, Koch M, Weitz J, Kleeff J, Friess H, Zöller M, Büchler MW, Z’graggen K.
Surgery. 2006 Jan;139(1):104-8.
Schmitz-Winnenthal FH, Volk C, Z’graggen K, Galindo L, Nummer D, Ziouta Y, Bucur M, Weitz J, Schirrmacher V, Büchler MW, Beckhove P.
Cancer Res. 2005 Nov 1;65(21):10079-87
Gesierich S, Paret C, Hildebrand D, Weitz J, Z’graggen K, Schmitz-Winnenthal FH, Horejsi V, Yoshie O, Herlyn D, Ashman LK, Zöller M.
Clin Cancer Res. 2005 Apr 15;11(8):2840-52.
Changes in morbidity after pancreatic resection: toward the end of completion pancreatectomy.
Büchler MW, Wagner M, Schmied BM, Uhl W, Friess H, Z’graggen K.
Arch Surg. 2003 Dec;138(12):1310-4
Promoting effect of a high-fat/high-protein diet in DMBA-induced ductal pancreatic cancer in rats.
Z’graggen K, Warshaw AL, Werner J, Graeme-Cook F, Jimenez RE, Fernández-Del Castillo C.
Ann Surg. 2001 May;233(5):688-95
Biological implications of tumor cells in blood and bone marrow of pancreatic cancer patients.
Z’graggen K, Centeno BA, Fernandez-del Castillo C, Jimenez RE, Werner J, Warshaw AL.
Surgery. 2001 May;129(5):537-46
Z’graggen K, Maurer CA, Kern B, Büchler MW.
Ann Surg. 2001 Dec;234(6):780-5
Werner J, Z’graggen K, Fernández-del Castillo C, Lewandrowski KB, Compton CC, Warshaw AL.
Ann Surg. 1999 Jun;229(6):834-40
Middle segment pancreatectomy: a novel technique for conserving pancreatic tissue.
Warshaw AL, Rattner DW, Fernández-del Castillo C, Z’graggen K.
Arch Surg. 1998 Mar;133(3):327-31
Metastases to the pancreas and their surgical extirpation.
Z’graggen K, Fernández-del Castillo C, Rattner DW, Sigala H, Warshaw AL.
Arch Surg. 1998 Apr;133(4):413-7
Cytotoxic cells are activated in cellular infiltrates of alcoholic chronic pancreatitis.
Hunger RE, Mueller C, Z’graggen K, Friess H, Büchler MW.
Gastroenterology. 1997 May;112(5):1656-63.
Z'Graggen K, Walz A, Mazzucchelli L, Strieter RM, Mueller C.
Gastroenterology. 1997 Sep;113(3):808-16.
Z’graggen K, Aronsky D, Maurer CA, Klaiber C, Baer HU.
Arch Surg. 1997 Sep;132(9):1026-30
Z’graggen K, Rivera JA, Compton CC, Pins M, Werner J, Fernández-del Castillo C, Rattner DW, Lewandrowski KB, Rustgi AK, Warshaw AL.
Ann Surg. 1997 Oct;226(4):491-8
THE TEAM OF THE Swiss Pancreas Institute
Enquiries and contact
Prof. Dr. med. Z'graggen and his team look forward to welcoming you to the Swiss Pancreas Institute. If you are unsure about our services or have any other questions, we are at your disposal: Get in touch.